Search on: CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PDE1 FAMILY 
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Descriptor English:   Cyclic Nucleotide Phosphodiesterases, Type 1 
Descriptor Spanish:   Fosfodiesterasas de Nucleótidos Cíclicos Tipo 1 
Descriptor Portuguese:   Nucleotídeo Cíclico Fosfodiesterase do Tipo 1 
Synonyms English:   Ca(2+)-CaM-Stimulated PDE
Ca++ Calmodulin Dependent Cyclic AMP Phosphodiesterase
Ca-CaM-Phosphodiesterase
Calcium-Calmodulin-Dependent Phosphodiesterase
Calcium-Calmodulin-Stimulated Cyclic AMP Phosphodiesterase
Calmodulin Phosphodiesterase
Calmodulin-Dependent Phosphodiesterase
Calmodulin-Dependent cGMP Phosphodiesterase
Cyclic Nucleotide Phosphodiesterase PDE1 Family
Cyclic Nucleotide Phosphodiesterases, Type 1A
Cyclic Nucleotide Phosphodiesterases, Type 1B
Cyclic Nucleotide Phosphodiesterases, Type 1C
PDE1 Phosphodiesterases
Phosphodiesterase 1A, Calmodulin-Dependent
Phosphodiesterase 1B, Calmodulin-Dependent
Phosphodiesterase 1C, Calmodulin-Dependent
Ca CaM Phosphodiesterase
Calcium Calmodulin Dependent Phosphodiesterase
Calcium Calmodulin Stimulated Cyclic AMP Phosphodiesterase
Calmodulin Dependent Phosphodiesterase
Calmodulin Dependent cGMP Phosphodiesterase
Calmodulin-Dependent Phosphodiesterase 1A
Calmodulin-Dependent Phosphodiesterase 1B
Calmodulin-Dependent Phosphodiesterase 1C
Phosphodiesterase 1A, Calmodulin Dependent
Phosphodiesterase 1B, Calmodulin Dependent
Phosphodiesterase 1C, Calmodulin Dependent
Phosphodiesterase, Calcium-Calmodulin-Dependent
Phosphodiesterase, Calmodulin-Dependent cGMP
Phosphodiesterases, PDE1
cGMP Phosphodiesterase, Calmodulin-Dependent
Cyclic Nucleotide Phosphodiesterases, Type I  
Tree Number:   D08.811.277.352.640.150.100
D08.811.277.352.640.155.100
D12.644.360.008.100
D12.644.360.009.100
D12.776.476.008.100
D12.776.476.009.100
Definition English:   A CALCIUM and CALMODULIN-dependent cyclic nucleotide phosphodiesterase subfamily. The three members of this family are referred to as type 1A, type 1B, and type 1C and are each product of a distinct gene. In addition, multiple enzyme variants of each subtype can be produced due to multiple alternative mRNA splicing. Although the type 1 enzymes are classified as 3',5'-cyclic-AMP phosphodiesterases (EC 3.1.4.17), some members of this class have additional specificity for CYCLIC GMP. 
History Note English:   2008(1981) for CA++ CALMODULIN DEPENDENT CYCLIC AMP PHOSPHODIESTERASE use 3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE 1986-2007, for CALMODULIN PHOSPHODIESTERASE use 3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE 1981-2007, for CALMODULIN-DEPENDENT PHOSPHODIESTERASE use 3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE 1984-2007 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52676 
Unique Identifier:   D054677 

Occurrence in VHL: 		 

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